Switching from Oral Cholinesterase Inhibitors to the Rivastigmine Transdermal Patch
نویسندگان
چکیده
منابع مشابه
Efficacy and Safety of Switching from Oral Cholinesterase Inhibitors to the Rivastigmine Transdermal Patch in Patients with Probable Alzheimer's Disease
BACKGROUND AND PURPOSE The goal of this study was to estimate the efficacy and safety of the rivastigmine transdermal patch in patients with probable Alzheimer's disease (AD) who cannot tolerate or do not respond to oral cholinesterase inhibitors (ChEIs). METHODS A 24-week, prospective, open-label, single-arm, multicenter study was conducted from June 2009 to June 2010 in patients with probab...
متن کاملSwitching from donepezil tablets to rivastigmine transdermal patch in Alzheimer's disease.
OBJECTIVE Evaluate safety and tolerability of switching from donepezil to rivastigmine transdermal patch in patients with mild to moderate Alzheimer's disease. METHODS Prospective, parallel-group, open-label study to evaluate immediate or delayed switch from 5-10 mg/day donepezil to 4.6 mg/24 h rivastigmine following a 4-week treatment period. RESULTS Rates of discontinuation due to any rea...
متن کاملAn Atypical Cutaneous Reaction to Rivastigmine Transdermal Patch
Rivastigmine is a cholinesterase inhibitor which improves cognitive function and is currently being used in patients with mild to moderate Parkinson's and Alzheimer's dementia. This drug can be given orally or topically, as transdermal patch. The latter form is currently used for most excellent compliance and few side effects. The most common cutaneous side effects are irritative dermatitis. We...
متن کاملPreparation and Characterization of Rivastigmine Transdermal Patch Based on Chitosan Microparticles
Here we report a novel approach for preparation of a 6-day transdermal drug delivery system (TDDS) as treatment for mild to moderate Alzheimer’s disease. The spray drying method was used to prepare microparticles containing the anti-Alzheimer drug. The content of the drug was determined by High Performance Liquid Chromatography (HPLC) method. The morphology and size range of the microparticles ...
متن کاملPreparation and Characterization of Rivastigmine Transdermal Patch Based on Chitosan Microparticles
Here we report a novel approach for preparation of a 6-day transdermal drug delivery system (TDDS) as treatment for mild to moderate Alzheimer’s disease. The spray drying method was used to prepare microparticles containing the anti-Alzheimer drug. The content of the drug was determined by High Performance Liquid Chromatography (HPLC) method. The morphology and size range of the microparticles ...
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ژورنال
عنوان ژورنال: CNS Neuroscience & Therapeutics
سال: 2010
ISSN: 1755-5930,1755-5949
DOI: 10.1111/j.1755-5949.2009.00119.x